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A Closer Look at Dark Toxicity of the Photosensitizer TMPyP in Bacteria

Eckl, Daniel B. ; Dengler, Linda ; Nemmert, Marina ; Eichner, Anja ; Bäumler, Wolfgang ; Huber, Harald


Photodynamic inactivation of bacteria (PIB) is based on photosensitizers which absorb light and generate reactive oxygen species (ROS), killing cells via oxidation. PIB is evaluated by comparing viability with and without irradiation, where reduction of viability in the presence of the photosensitizer without irradiation is considered as dark toxicity. This effect is controversially discussed for ...


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