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High pressure response of 1H NMR chemical shifts of purine nucleotides

Munte, Claudia E. ; Karl, Matthias ; Kauter, Waldemar ; Eberlein, Lukas ; Pham, Thuy-Vy ; Erlach, Markus Beck ; Kast, Stefan M. ; Kremer, Werner ; Kalbitzer, Hans Robert


The study of the pressure response by NMR spectroscopy provides information on the thermodynamics of conformational equilibria in proteins and nucleic acids. For obtaining a database for expected pressure effects on free nucleotides and nucleotides bound in macromolecular complexes, the pressure response of H-1 chemical shifts and J-coupling constants of the purine 5'-ribonucleotides AMP, ADP, ...


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