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Value of fluid‐attenuated inversion recovery MRI data analyzed by the lesion segmentation toolbox in amyotrophic lateral sclerosis

Wirth, Anna M. ; Johannesen, Siw ; Khomenko, Andrei ; Baldaranov, Dobri ; Bruun, Tim‐Henrik ; Wendl, Christina ; Schuierer, Gerhard ; Greenlee, Mark W. ; Bogdahn, Ulrich



Abstract

Background MRI fluid-attenuated inversion recovery (FLAIR) studies reported hyperintensity in the corticospinal tract and corpus callosum of patients with amyotrophic lateral sclerosis (ALS). Purpose To evaluate the lesion segmentation toolbox (LST) for the objective quantification of FLAIR lesions in ALS patients. Study Type Retrospective. Population Twenty-eight ALS patients (eight females, ...

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