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Glomerular expression pattern of long non-coding RNAs in the type 2 diabetes mellitus BTBR mouse model

Reichelt-Wurm, Simone ; Wirtz, Tobias ; Chittka, Dominik ; Lindenmeyer, Maja ; Reichelt, Robert M. ; Beck, Sebastian ; Politis, Panagiotis ; Charonis, Aristidis ; Kretz, Markus ; Huber, Tobias B. ; Liu, Shuya ; Banas, Bernhard ; Banas, Miriam C.


The prevalence of type 2 diabetes mellitus (T2DM) and by association diabetic nephropathy (DN) will continuously increase in the next decades. Nevertheless, the underlying molecular mechanisms are largely unknown and studies on the role of new actors like long non-coding RNAs (lncRNAs) barely exist. In the present study, the inherently insulin-resistant mouse strain "black and tan, brachyuric" ...


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