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Association between physical activity and risk of hepatobiliary cancers: A multinational cohort study

Baumeister, Sebastian E. ; Schlesinger, Sabrina ; Aleksandrova, Krasimira ; Jochem, Carmen ; Jenab, Mazda ; Gunter, Marc J. ; Overvad, Kim ; Tjønneland, Anne ; Boutron-Ruault, Marie-Christine ; Carbonnel, Franck ; Fournier, Agnès ; Kühn, Tilman ; Kaaks, Rudolf ; Pischon, Tobias ; Boeing, Heiner ; Trichopoulou, Antonia ; Bamia, Christina ; La Vecchia, Carlo ; Masala, Giovanna ; Panico, Salvatore ; Fasanelli, Francesca ; Tumino, Rosario ; Grioni, Sara ; Bueno de Mesquita, Bas ; Vermeulen, Roel ; May, Anne M. ; Borch, Kristin B. ; Oyeyemi, Sunday O. ; Ardanaz, Eva ; Rodríguez-Barranco, Miguel ; Dolores Chirlaque López, María ; Felez-Nobrega, Mireia ; Sonestedt, Emily ; Ohlsson, Bodil ; Hemmingsson, Oskar ; Werner, Mårten ; Perez-Cornago, Aurora ; Ferrari, Pietro ; Stepien, Magdalena ; Freisling, Heinz ; Tsilidis, Konstantinos K. ; Ward, Heather ; Riboli, Elio ; Weiderpass, Elisabete ; Leitzmann, Michael F.



Zusammenfassung

Background & Aims: To date, evidence on the association between physical activity and risk of hepatobiliary cancers has been inconclusive. Weexamined this association in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC). Methods: We identified 275 hepatocellular carcinoma (HCC) cases, 93 intrahepatic bile duct cancers (IHBCs), and 164 non-gallbladder extrahepatic bile ...

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