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Aerobic exercise increases hippocampal subfield volumes in younger adults and prevents volume decline in the elderly

Frodl, Thomas ; Strehl, Katharina ; Carballedo, Angela ; Tozzi, Leonardo ; Doyle, Myles ; Amico, Francesco ; Gormley, John ; Lavelle, Grace ; O’Keane, Veronica


Exercise improves both physical and mental health and increases neurogenesis in the dendate gyrus (DG) of the hippocampus. The aim of this study was to examine whether exercising, as compared to no change in regular physical activity, would impact on hippocampal volume, and in particular the core hippocampal structures, DG and cornu ammonis (CA) subfields, and whether any changes would be ...


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