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Physical activity and risk of Alzheimer disease

Baumeister, Sebastian E. ; Karch, André ; Bahls, Martin ; Teumer, Alexander ; Leitzmann, Michael F. ; Baurecht, Hansjörg



Abstract

Objective Evidence from observational studies for the effect of physical activity on the risk of Alzheimer disease (AD) is inconclusive. We performed a 2-sample mendelian randomization analysis to examine whether physical activity is protective for AD. Methods Summary data of genome-wide association studies on physical activity and AD were used. The primary study population included 21,982 ...

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