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3D In Vivo Models for Translational Research on Pancreatic Cancer: The Chorioallantoic Membrane (CAM) Model

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Pion, Eric ; Karnosky, Julia ; Boscheck, Sofie ; Wagner, Benedikt J. ; Schmidt, Katharina M. ; Brunner, Stefan M. ; Schlitt, Hans J. ; Aung, Thiha ; Hackl, Christina ; Haerteis, Silke
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Date of publication of this fulltext: 17 Aug 2022 08:32


Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with adverse outcomes that have barely improved over the last decade. About half of all patients present with metastasis at the time of diagnosis, and the 5-year overall survival rate across all stages is only 6%. Innovative in vivo research models are necessary to combat this cancer and to discover novel treatment strategies. ...


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