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Development of a Neurotensin-Derived 68Ga-Labeled PET Ligand with High In Vivo Stability for Imaging of NTS1 Receptor-Expressing Tumors

URN to cite this document:
urn:nbn:de:bvb:355-epub-530105
DOI to cite this document:
10.5283/epub.53010
Schindler, Lisa ; Moosbauer, Jutta ; Schmidt, Daniel ; Spruss, Thilo ; Grätz, Lukas ; Lüdeke, Steffen ; Hofheinz, Frank ; Meister, Sebastian ; Echtenacher, Bernd ; Bernhardt, Günther ; Pietzsch, Jens ; Hellwig, Dirk ; Keller, Max
[img]License: Creative Commons Attribution 4.0
PDF - Accepted Version
(1MB)
Date of publication of this fulltext: 10 Oct 2022 13:14



Abstract

Simple Summary Cancer diagnostics based on molecular imaging techniques such as positron emission tomography (PET) requires radiolabeled tracers, which are taken up by tumors. As the neurotensin receptor type 1 (NTS1R) is present in certain malignant tumors, radiolabeled NTS1R ligands can serve as molecular tools for tumor imaging. A straightforward approach for developing NTS1R PET ligands would ...

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