Seliger, Corinna ; Meyer, Anne-Louise ; Leidgens, Verena ; Rauer, Lisa ; Moeckel, Sylvia ; Jachnik, Birgitt ; Proske, Judith ; Dettmer, Katja ; Rothhammer-Hampl, Tanja ; Kaulen, Leon D. ; Riemenschneider, Markus J. ; Oefner, Peter J. ; Kreutz, Marina 
; Schmidt, Nils-Ole ; Merrill, Marsha ; Uhl, Martin ; Renner, Kathrin ; Vollmann-Zwerenz, Arabel ; Proescholdt, Martin A. ; Hau, Peter
; Schmidt, Nils-Ole ; Merrill, Marsha ; Uhl, Martin ; Renner, Kathrin ; Vollmann-Zwerenz, Arabel ; Proescholdt, Martin A. ; Hau, Peter 
Zusammenfassung
Brain-tumor-initiating cells (BTICs) of proneural and mesenchymal origin contribute to the highly malignant phenotype of glioblastoma (GB) and resistance to current therapies. BTICs of different subtypes were challenged with oxidative phosphorylation (OXPHOS) inhibition with metformin to assess the differential effects of metabolic intervention on key resistance features. Whereas mesenchymal ...
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