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Cardiovascular Risk Factor Control in 70- to 95-Year-Old Individuals: Cross-Sectional Results from the Population-Based AugUR Study
Donhauser, Ferdinand J., Zimmermann, Martina E.
, Steinkirchner, Anna B., Wiegrebe, Simon, Dietl, Alexander, Brandl, Caroline
, Burkhardt, Ralph
, Gessner, André, Schweda, Frank, Bergler, Tobias, Schäffner, Elke
, Böger, Carsten A., Kronenberg, Florian
, Luchner, Andreas, Stark, Klaus J. und Heid, Iris M.
(2023)
Cardiovascular Risk Factor Control in 70- to 95-Year-Old Individuals: Cross-Sectional Results from the Population-Based AugUR Study.
Journal of Clinical Medicine 12 (6), S. 2102.
Veröffentlichungsdatum dieses Volltextes: 08 Mrz 2023 14:56
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.53910
Zusammenfassung
Cardiovascular risk factors such as high glucose, LDL-cholesterol, blood pressure, and impaired kidney function are particularly frequent in old-aged individuals. However, population-based data on the extent of cardiovascular risk factor control in the old-aged population is limited. AugUR is a cohort of the mobile "70+"-year-old population of/near Regensburg, recruited via population registries. ...
Cardiovascular risk factors such as high glucose, LDL-cholesterol, blood pressure, and impaired kidney function are particularly frequent in old-aged individuals. However, population-based data on the extent of cardiovascular risk factor control in the old-aged population is limited. AugUR is a cohort of the mobile "70+"-year-old population of/near Regensburg, recruited via population registries. We conducted cross-sectional analyses assessing the proportion of AugUR participants with LDL-cholesterol, HbA1c, or blood pressure beyond recommended levels and their association with impaired creatinine- and cystatin-based estimated glomerular filtration rate (eGFR, <60 mL/min/1.73 m(2)) or urine albumin-creatinine ratio (UACR, >= 30 mg/g). Among 2215 AugUR participants, 74.7% were taking lipid-, glucose-, blood-pressure-lowering, or diuretic medication. High LDL-cholesterol at >= 116 mg/dL was observed for 76.1% (51.1% among those with prior cardiovascular events). We found HbA1c >= 7.0% for 6.3%, and high or low systolic blood pressure for 6.8% or 26.5%, respectively (>= 160, <120 mmHg). Logistic regression revealed (i) high HbA1c levels associated with increased risk for impaired kidney function among those untreated, (ii) high blood pressure with increased UACR, and (iii) low blood pressure with impaired eGFR, which was confined to individuals taking diuretics. Our results provide important insights into cardiovascular risk factor control in individuals aged 70-95 years, which are understudied in most population-based studies.
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| Dokumentenart | Artikel | ||||
| Titel eines Journals oder einer Zeitschrift | Journal of Clinical Medicine | ||||
| Verlag: | MDPI | ||||
|---|---|---|---|---|---|
| Ort der Veröffentlichung: | BASEL | ||||
| Band: | 12 | ||||
| Nummer des Zeitschriftenheftes oder des Kapitels: | 6 | ||||
| Seitenbereich: | S. 2102 | ||||
| Datum | 7 März 2023 | ||||
| Institutionen | Medizin > Lehrstuhl für Augenheilkunde Medizin > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie) Medizin > Abteilung für Nephrologie Medizin > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin Medizin > Lehrstuhl für Medizinische Mikrobiologie und Hygiene Medizin > Institut für Epidemiologie und Präventivmedizin > Lehrstuhl für Genetische Epidemiologie Biologie und Vorklinische Medizin > Institut für Physiologie > Prof. Dr. Frank Schweda | ||||
| Identifikationsnummer |
| ||||
| Stichwörter / Keywords | DENSITY-LIPOPROTEIN CHOLESTEROL; GERMAN HEALTH INTERVIEW; BLOOD-PRESSURE; ADULTS; OLDER; ASSOCIATION; PREVALENCE; MANAGEMENT; MORTALITY; COHORT; LDL-cholesterol; HbA1c; blood pressure; estimated glomerular filtration rate; urine albumin to creatinine ratio; elderly population | ||||
| Dewey-Dezimal-Klassifikation | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin | ||||
| Status | Veröffentlicht | ||||
| Begutachtet | Ja, diese Version wurde begutachtet | ||||
| An der Universität Regensburg entstanden | Ja | ||||
| URN der UB Regensburg | urn:nbn:de:bvb:355-epub-539101 | ||||
| Dokumenten-ID | 53910 |
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