Innate immunity and early liver inflammation

URN to cite this document:: urn:nbn:de:bvb:355-epub-541679
DOI to cite this document:: 10.5283/epub.54167

Yang Zhou, Jordi

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 09 May 2023 05:47

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Abstract

The innate system constitutes a first-line defence mechanism against pathogens. 80% of the blood supply entering the human liver arrives from the splanchnic circulation through the portal vein, so it is constantly exposed to immunologically active substances and pathogens from the gastrointestinal tract. Rapid neutralization of pathogens and toxins is an essential function of the liver, but so ...