Nanadikar, Maithily S. ; Vergel Leon, Ana M. ; Guo, Jia ; van Belle, Gijsbert J. ; Jatho, Aline ; Philip, Elvina S. ; Brandner, Astrid F. ; Böckmann, Rainer A. ; Shi, Runzhu ; Zieseniss, Anke ; Siemssen, Carla M. ; Dettmer, Katja 
; Brodesser, Susanne ; Schmidtendorf, Marlen ; Lee, Jingyun ; Wu, Hanzhi ; Furdui, Cristina M. ; Brandenburg, Sören ; Burgoyne, Joseph R. ; Bogeski, Ivan ; Riemer, Jan ; Chowdhury, Arpita ; Rehling, Peter ; Bruegmann, Tobias ; Belousov, Vsevolod V. ; Katschinski, Dörthe M.
; Brodesser, Susanne ; Schmidtendorf, Marlen ; Lee, Jingyun ; Wu, Hanzhi ; Furdui, Cristina M. ; Brandenburg, Sören ; Burgoyne, Joseph R. ; Bogeski, Ivan ; Riemer, Jan ; Chowdhury, Arpita ; Rehling, Peter ; Bruegmann, Tobias ; Belousov, Vsevolod V. ; Katschinski, Dörthe M. 
Abstract
Protein targets that are affected by ROS and underly impaired inotropic effects in the heart are largely unknown. Here, the authors identify the gamma-subunit of IDH3 as a redox switch linking oxidative stress to impaired metabolism and heart function. Redox signaling and cardiac function are tightly linked. However, it is largely unknown which protein targets are affected by hydrogen peroxide ...
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