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Multivariate Struktur-Wirkungs-Analyse (QSWA) für Enzyminduktoren: Polychlorierte Biphenyle

Franke, R. ; Schwarz, G. ; Dove, Stefan ; Dietrich, A. ; Klinger, W.


Data on PCB induction of liver enzymes (pentobarbital sleep time, carboxylesterase, and microsomal aniline hydroxylase, p-nitroanisole O-demethylase, aminopyrine N-demethylase and nitrobenzoic acid reductase) (Johnstone, G. J., et al., 1974) were used for QSAR anal. with the parameters mol. wt., total no. of Cl atoms, mol. symmetry (2 parameters), and position of the Cl substituents (7 ...


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