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Saturated Fat-Mediated Upregulation of IL-32 and CCL20 in Hepatocytes Contributes to Higher Expression of These Fibrosis-Driving Molecules in MASLD

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Schilcher, Katharina ; Dayoub, Rania ; Kubitza, Marion ; Riepl, Jakob ; Klein, Kathrin ; Buechler, Christa ; Melter, Michael ; Weiss, Thomas S.
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Date of publication of this fulltext: 30 Aug 2023 09:18


Metabolic dysfunction-associated steatotic liver disease (MASLD) comprises a spectrum of liver diseases, ranging from liver steatosis to metabolic dysfunction-associated steatohepatitis (MASH), increasing the risk of developing cirrhosis and hepatocellular carcinoma (HCC). Fibrosis within MASLD is critical for disease development; therefore, the identification of fibrosis-driving factors is ...


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