Saturated Fat-Mediated Upregulation of IL-32 and CCL20 in Hepatocytes Contributes to Higher Expression of These Fibrosis-Driving Molecules in MASLD

URN to cite this document:: urn:nbn:de:bvb:355-epub-546573
DOI to cite this document:: 10.5283/epub.54657

Schilcher, Katharina ; Dayoub, Rania

; Kubitza, Marion ; Riepl, Jakob ; Klein, Kathrin ; Buechler, Christa

; Melter, Michael

; Weiss, Thomas S.

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 30 Aug 2023 09:18

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Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) comprises a spectrum of liver diseases, ranging from liver steatosis to metabolic dysfunction-associated steatohepatitis (MASH), increasing the risk of developing cirrhosis and hepatocellular carcinoma (HCC). Fibrosis within MASLD is critical for disease development; therefore, the identification of fibrosis-driving factors is ...