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Nöldner, Philipp ; Burger, Martin ; Garcke, Harald

Sharp interface analysis of a diffuse interface model for cell blebbing with linker dynamics

Nöldner, Philipp, Burger, Martin and Garcke, Harald (2023) Sharp interface analysis of a diffuse interface model for cell blebbing with linker dynamics. ZAMM - Journal of Applied Mathematics and Mechanics / Zeitschrift für Angewandte Mathematik und Mechanik.

Date of publication of this fulltext: 19 Sep 2023 09:36
Article
DOI to cite this document: 10.5283/epub.54700


Abstract

We investigate the convergence of solutions of a recently proposed diffuse interface/phase field model for cell blebbing by means of matched asymptotic expansions. It is a biological phenomenon that increasingly attracts attention by both experimental and theoretical communities. Key to understanding the process of cell blebbing mechanically are proteins that link the cell cortex and the cell ...

We investigate the convergence of solutions of a recently proposed diffuse interface/phase field model for cell blebbing by means of matched asymptotic expansions. It is a biological phenomenon that increasingly attracts attention by both experimental and theoretical communities. Key to understanding the process of cell blebbing mechanically are proteins that link the cell cortex and the cell membrane. Another important model component is the bending energy of the cell membrane and cell cortex which accounts for differential equations up to sixth order. Both aspects pose interesting mathematical challenges that will be addressed in this work like showing non-singularity formation for the pressure at boundary layers, deriving equations for asymptotic series coefficients of uncommonly high order, and dealing with a highly coupled system of equations.



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Details

Item typeArticle
Journal or Publication TitleZAMM - Journal of Applied Mathematics and Mechanics / Zeitschrift für Angewandte Mathematik und Mechanik
Publisher:WILEY-V C H VERLAG GMBH
Place of Publication:WEINHEIM
Date12 September 2023
InstitutionsMathematics > Prof. Dr. Harald Garcke
Identification Number
ValueType
10.1002/zamm.202300101DOI
KeywordsBLEBS
Dewey Decimal Classification500 Science > 510 Mathematics
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgPartially
URN of the UB Regensburgurn:nbn:de:bvb:355-epub-547009
Item ID54700

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