Go to content
UR Home

Carboplatin derivatives with superior antitumor activity compared to the parent compound

Bernhardt, Günther ; Brunner, Henri ; Gruber, Nick ; Lottner, Christian ; Pushpan, Simi K. ; Tsuno, Takashi ; Zabel, Manfred


A series of new carboplatin derivs. was synthesized by introducing fluoro, chloro, bromo and hydroxy substituents into the cyclobutane ring. The carboxylic acid groups were used for the complexation with platinum(II) fragments bearing two ammonia and (RR/SS)-trans-1,2-diaminocyclohexane ligands, resp., as non-leaving groups. The antiproliferative activity of the new carboplatin analogs differing ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons