Lux, Franz, Hollstein, Michael, Reile, Herta, Bernhardt, Günther und Schönenberger, Helmut (1996) Discrepancy between cytotoxicity, platinum accumulation, and DNA platination in MCF-7 breast cancer cells treated with diaqua(1,2-diphenylethylenediamine) platinum(II) sulfates and cisplatin. Biological Trace Element Research 53 (1-3), S. 113-128.
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Zusammenfassung
Cisplatin (cis), racemic-diaqua[1,2-bis(4-fluorophenyl)ethylenediamine]platinum(II) sulfate (r-4F-PtSO4), meso-diaqua[1,2-bis(4-fluorophenyl)ethylenediamine]platinum(II) sulfate (m-4F-PtSO4), and meso-diaqua[1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]platinum(II) sulfate (m-2,6Cl2-4OH-PtSO4) were compared with regard to their growth inhibitory effect on MCF-7 breast cancer cells. At ...
Bibliographische Daten exportieren
| Dokumentenart: | Artikel | ||||
|---|---|---|---|---|---|
| Datum: | 1996 | ||||
| Zusätzliche Informationen (Öffentlich): | CAN 125:211942 1-6 Pharmacology 15663-27-1 (Cisplatin); 105856-32-4; 105856-34-6; 125948-93-8 Role: BAC (Biological activity or effector, except adverse), BPR (Biological process), BSU (Biological study, unclassified), THU (Therapeutic use), BIOL (Biological study), PROC (Process), USES (Uses) (discrepancy between cytotoxicity and platinum accumulation and DNA platination in MCF-7 breast cancer cells treated with diaqua(diphenylethylenediamine) platinum(II) sulfates and cisplatin in MCF-7 human breast cancer cells); 7440-06-4 (Platinum) Role: BPR (Biological process), BSU (Biological study, unclassified), MFM (Metabolic formation), BIOL (Biological study), FORM (Formation, nonpreparative), PROC (Process) (discrepancy between cytotoxicity and platinum accumulation and DNA platination in MCF-7 breast cancer cells treated with diaqua(diphenylethylenediamine) platinum(II) sulfates and cisplatin in MCF-7 human breast cancer cells) | ||||
| Institutionen: | Chemie und Pharmazie > Institut für Pharmazie > Entpflichtete oder im Ruhestand befindliche Professoren > Prof. Schönenberger Chemie und Pharmazie > Institut für Pharmazie > Lehrstuhl Pharmazeutische / Medizinische Chemie II (Prof. Buschauer) | ||||
| Identifikationsnummer: |
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| Stichwörter / Keywords: | Neoplasm inhibitors (discrepancy between cytotoxicity and platinum accumulation and DNA platination in MCF-7 breast cancer cells treated with diaqua(diphenylethylenediamine); platinum(II) sulfates and cisplatin in MCF-7 human breast cancer cells); Deoxyribonucleic acids Role: BPR (Biological process), BSU (Biological study, unclassified), BIOL (Biological study), PROC (Process) (discrepancy between cytotoxicity and platinum accumulation and DNA platination in MCF-7 breast cancer cells treated with diaqua(diphenylethylenediamine) platinum(II) sulfates and cisplatin in MCF-7 human breast cancer cells) platinum compd cytotoxicity DNA platination tumor diaquadiphenylethylenediamine platinum cytotoxicity DNA platination tumor | ||||
| Dewey-Dezimal-Klassifikation: | 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie 500 Naturwissenschaften und Mathematik > 540 Chemie | ||||
| Status: | Veröffentlicht | ||||
| Begutachtet: | Ja, diese Version wurde begutachtet | ||||
| An der Universität Regensburg entstanden: | Zum Teil | ||||
| Eingebracht am: | 15 Jan 2009 15:37 | ||||
| Zuletzt geändert: | 08 Mrz 2017 08:20 | ||||
| Dokumenten-ID: | 5481 |
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