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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-549550
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.54955
Zusammenfassung
DEAD-box RNA helicases are implicated in most aspects of RNA biology, where these enzymes unwind short RNA duplexes in an ATP-dependent manner. During the central step of the unwinding cycle, the two domains of the helicase core form a distinct closed conformation that destabilizes the RNA duplex, which ultimately leads to duplex melting. Despite the importance of this step for the unwinding ...
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