- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-550289
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.55028
Zusammenfassung
Background:Genetic variants at the TRIB1 gene locus are strongly associated with plasma lipid traits and the risk of coronary artery disease in humans. Here, we analyzed the consequences of Trib1 deficiency on lipid metabolism and atherosclerotic lesion formation in atherosclerosis-susceptible Ldlr(-/-) mice. Methods:Trib1(-/-) mice were crossed onto the Ldlr(-/-) background to generate ...
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