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Shedding Light on the D1‐Like Receptors: A Fluorescence‐Based Toolbox for Visualization of the D1 and D5 Receptors

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Rosier, Niklas ; Moennich, Denise ; Nagl, Martin ; Schihada, Hannes ; Sirbu, Alexei ; Konar, Nergis ; Reyes-Resina, Irene ; Navarro, Gemma ; Franco, Rafael ; Kolb, Peter ; Annibale, Paolo ; Pockes, Steffen
Date of publication of this fulltext: 22 Nov 2023 07:56

This publication is part of the DEAL contract with Wiley.


Dopamine D1-like receptors are the most abundant type of dopamine receptors in the central nervous system and, even after decades of discovery, still highly interesting for the study of neurological diseases. We herein describe the synthesis of a new set of fluorescent ligands, structurally derived from D1R antagonist SCH-23390 and labeled with two different fluorescent dyes, as tool compounds ...


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