Fluorescent Tools for the Imaging of Dopamine D2‐Like Receptors

URN to cite this document:: urn:nbn:de:bvb:355-epub-550586
DOI to cite this document:: 10.5283/epub.55058

Nagl, Martin ; Moennich, Denise ; Rosier, Niklas

; Schihada, Hannes ; Sirbu, Alexei ; Konar, Nergis ; Reyes-Resina, Irene ; Navarro, Gemma ; Franco, Rafael ; Kolb, Peter ; Annibale, Paolo ; Pockes, Steffen

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Date of publication of this fulltext: 22 Nov 2023 08:50

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Abstract

The family of dopamine D2-like receptors represents an interesting target for a variety of neurological diseases, e. g. Parkinson's disease (PD), addiction, or schizophrenia. In this study we describe the synthesis of a new set of fluorescent ligands as tools for visualization of dopamine D2-like receptors. Pharmacological characterization in radioligand binding studies identified UR-MN212 (20) ...