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Gene Coexpression Network Reveals Highly Conserved, Well-Regulated Anti-Ageing Mechanisms in Old Ant Queens

Harrison, Mark C ; Niño, Luisa M Jaimes ; Rodrigues, Marisa Almeida ; Ryll, Judith ; Flatt, Thomas ; Oettler, Jan ; Bornberg-Bauer, Erich ; Eyre-Walker, Adam


Evolutionary theories of ageing predict a reduction in selection efficiency with age, a so-called "selection shadow," due to extrinsic mortality decreasing effective population size with age. Classic symptoms of ageing include a deterioration in transcriptional regulation and protein homeostasis. Understanding how ant queens defy the trade-off between fecundity and lifespan remains a major ...


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