Physical activity, sedentary behavior and risk of coronary artery disease, myocardial infarction and ischemic stroke: a two-sample Mendelian randomization study

URN to cite this document:: urn:nbn:de:bvb:355-epub-564967
DOI to cite this document:: 10.5283/epub.56496

Bahls, Martin

; Leitzmann, Michael F. ; Karch, André

; Teumer, Alexander

; Dörr, Marcus ; Felix, Stephan B. ; Meisinger, Christa ; Baumeister, Sebastian E. ; Baurecht, Hansjörg

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 29 Feb 2024 12:28

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Abstract

Aims Observational evidence suggests that physical activity (PA) is inversely and sedentarism positively related with cardiovascular disease risk. We performed a two-sample Mendelian randomization (MR) analysis to examine whether genetically predicted PA and sedentary behavior are related to coronary artery disease, myocardial infarction, and ischemic stroke. Methods and results We used single ...