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Altered hypothalamic DNA methylation and stress-induced hyperactivity following early life stress

Fitzgerald, Eamon ; Sinton, Matthew C. ; Wernig-Zorc, Sara ; Morton, Nicholas M. ; Holmes, Megan C. ; Boardman, James P. ; Drake, Amanda J.


Exposure to early life stress (ELS) during childhood or prenatally increases the risk of future psychiatric disorders. The effect of stress exposure during the neonatal period is less well understood. In preterm infants, exposure to invasive procedures is associated with altered brain development and future stress responses suggesting that the neonatal period could be a key time for the ...


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