Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors
Andreev, Stanislav, Pantsar, Tatu, Tesch, Roberta, Kahlke, Niclas, El-Gokha, Ahmed, Ansideri, Francesco, Grätz, Lukas, Romasco, Jenny, Sita, Giulia, Geibel, Christian
, Lämmerhofer, Michael, Tarozzi, Andrea, Knapp, Stefan
, Laufer, Stefan A. and Koch, Pierre
(2022)
Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors.
Journal of Medicinal Chemistry 65 (2), pp. 1283-1301.
Date of publication of this fulltext: 29 Feb 2024 12:56
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| Item type | Article | ||||
| Journal or Publication Title | Journal of Medicinal Chemistry | ||||
| Publisher: | AMER CHEMICAL SOC | ||||
|---|---|---|---|---|---|
| Place of Publication: | WASHINGTON | ||||
| Volume: | 65 | ||||
| Number of Issue or Book Chapter: | 2 | ||||
| Page Range: | pp. 1283-1301 | ||||
| Date | 2022 | ||||
| Institutions | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer) | ||||
| Identification Number |
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| Keywords | ORGANIC-MOLECULES; PROTEIN; KINASE; THERMODYNAMICS; RECOGNITION; SELECTIVITY; PREDICTION; DISCOVERY; SOLVENT; CELL | ||||
| Dewey Decimal Classification | 500 Science > 540 Chemistry & allied sciences 600 Technology > 610 Medical sciences Medicine 600 Technology > 615 Pharmacy | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| Item ID | 57463 |
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