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Andreev, Stanislav ; Pantsar, Tatu ; Tesch, Roberta ; Kahlke, Niclas ; El-Gokha, Ahmed ; Ansideri, Francesco ; Grätz, Lukas ; Romasco, Jenny ; Sita, Giulia ; Geibel, Christian ; Lämmerhofer, Michael ; Tarozzi, Andrea ; Knapp, Stefan ; Laufer, Stefan A. ; Koch, Pierre

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors

Andreev, Stanislav, Pantsar, Tatu, Tesch, Roberta, Kahlke, Niclas, El-Gokha, Ahmed, Ansideri, Francesco, Grätz, Lukas, Romasco, Jenny, Sita, Giulia, Geibel, Christian , Lämmerhofer, Michael, Tarozzi, Andrea, Knapp, Stefan , Laufer, Stefan A. and Koch, Pierre (2022) Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors. Journal of Medicinal Chemistry 65 (2), pp. 1283-1301.

Date of publication of this fulltext: 29 Feb 2024 12:56
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Item typeArticle
Journal or Publication TitleJournal of Medicinal Chemistry
Publisher:AMER CHEMICAL SOC
Place of Publication:WASHINGTON
Volume:65
Number of Issue or Book Chapter:2
Page Range:pp. 1283-1301
Date2022
InstitutionsChemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number
ValueType
10.1021/acs.jmedchem.0c02146DOI
KeywordsORGANIC-MOLECULES; PROTEIN; KINASE; THERMODYNAMICS; RECOGNITION; SELECTIVITY; PREDICTION; DISCOVERY; SOLVENT; CELL
Dewey Decimal Classification500 Science > 540 Chemistry & allied sciences
600 Technology > 610 Medical sciences Medicine
600 Technology > 615 Pharmacy
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgYes
Item ID57463

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