Sekar, Divya ; Dillmann, Christina ; Sirait-Fischer, Evelyn ; Fink, Annika F. ; Zivkovic, Aleksandra ; Baum, Natalie ; Strack, Elisabeth ; Klatt, Stephan 
; Zukunft, Sven ; Wallner, Stefan ; Descot, Arnaud ; Olesch, Catherine ; da Silva, Priscila ; von Knethen, Andreas ; Schmid, Tobias ; Grösch, Sabine ; Savai, Rajkumar ; Ferreirós, Nerea ; Fleming, Ingrid ; Ghosh, Sourav ; Rothlin, Carla V. ; Stark, Holger ; Medyouf, Hind ; Brüne, Bernhard ; Weigert, Andreas
; Zukunft, Sven ; Wallner, Stefan ; Descot, Arnaud ; Olesch, Catherine ; da Silva, Priscila ; von Knethen, Andreas ; Schmid, Tobias ; Grösch, Sabine ; Savai, Rajkumar ; Ferreirós, Nerea ; Fleming, Ingrid ; Ghosh, Sourav ; Rothlin, Carla V. ; Stark, Holger ; Medyouf, Hind ; Brüne, Bernhard ; Weigert, Andreas 
Abstract
An altered lipidome in tumors may affect not only tumor cells themselves but also their microenvironment. In this study, a lipidomics screen reveals increased amounts of phosphatidylser-ine (PS), particularly ether-PS (ePS), in murine mammary tumors compared with normal tissue. PS was produced by phosphatidylserine synthase 1 (PTDSS1), and depletion of Ptdss1 from tumor cells in mice reduced ePS ...
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