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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-592880
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.59288
Zusammenfassung
The overall significance of loop motions for enzymatic activity is generally accepted. However, it has largely remained unclear whether and how such motions can control different steps of catalysis. We have studied this problem on the example of the mobile active site β1α1-loop (loop1) of the (βα)8-barrel enzyme HisF, which is the cyclase subunit of imidazole glycerol phosphate synthase. Loop1 ...
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