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In vitro structure-toxicity relationship of chalcones in human hepatic stellate cells

Zenger, Katharina ; Dutta, Subhajit ; Wolff, Horst ; Genton, Marc G. ; Kraus, Birgit



Zusammenfassung

Xanthohumol (XN), the major prenylated chalcone from hops (Humulus lupulus L.), has received much attention within the last years, due to its multiple pharmacological activities including anti-proliferative, anti-inflammatory, antioxidant, pro-apoptotic, anti-bacterial and anti-adhesive effects. However, there exists a huge number of metabolites and structurally-related chalcones, which can be ...

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