Amine substitution of quinazolinones leads to selective nanomolar AChE inhibitors with ‘inverted’ binding mode
Darras, Fouad H., Wehle, Sarah, Huang, Guozheng
, Sotriffer, Christoph A. and Decker, Michael
(2014)
Amine substitution of quinazolinones leads to selective nanomolar AChE inhibitors with ‘inverted’ binding mode.
Bioorganic & Medicinal Chemistry 22 (17), pp. 4867-4881.
Date of publication of this fulltext: 19 Dec 2024 08:07
Article
Alternative links to fulltext
Involved Institutions
Details
| Item type | Article | ||||
| Journal or Publication Title | Bioorganic & Medicinal Chemistry | ||||
| Publisher: | PERGAMON-ELSEVIER SCIENCE LTD | ||||
|---|---|---|---|---|---|
| Place of Publication: | OXFORD | ||||
| Volume: | 22 | ||||
| Number of Issue or Book Chapter: | 17 | ||||
| Page Range: | pp. 4867-4881 | ||||
| Date | 2014 | ||||
| Institutions | Chemistry and Pharmacy > Institute of Pharmacy | ||||
| Identification Number |
| ||||
| Keywords | NITROGEN-BRIDGEHEAD COMPOUNDS; EMPIRICAL SCORING FUNCTIONS; ACETYLCHOLINESTERASE INHIBITORS; CHOLINESTERASE-INHIBITORS; ALZHEIMERS-DISEASE; GENETIC ALGORITHM; IDENTIFICATION; ALKALOIDS; COGNITION; DOCKING; Alzheimer's disease; Cholinesterase inhibitors; Computational study; Heterocycles; Quinazolinones | ||||
| Dewey Decimal Classification | 600 Technology > 615 Pharmacy | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| Item ID | 61205 |
Export bibliographical data
Owner only: item control page
Altmetric
Altmetric