| Dokumentenart: | Artikel | ||||
|---|---|---|---|---|---|
| Titel eines Journals oder einer Zeitschrift: | Proceedings of the National Academy of Sciences | ||||
| Verlag: | NATL ACAD SCIENCES | ||||
| Ort der Veröffentlichung: | WASHINGTON | ||||
| Band: | 110 | ||||
| Nummer des Zeitschriftenheftes oder des Kapitels: | 4 | ||||
| Seitenbereich: | S. 1369-1374 | ||||
| Datum: | 2013 | ||||
| Institutionen: | Biologie und Vorklinische Medizin > Institut für Zoologie Biologie und Vorklinische Medizin > Institut für Zoologie > Evolutionäre Ökologie (Prof. Dr. Erhard Strohm) Biologie und Vorklinische Medizin > Institut für Zoologie > Chemische Ökologie (Prof. Dr. Joachim Ruther) Chemie und Pharmazie > Institut für Organische Chemie Chemie und Pharmazie > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser | ||||
| Identifikationsnummer: |
| ||||
| Stichwörter / Keywords: | CURRANT STEM GIRDLER; SERRATIA-MARCESCENS; PERIPLANETA-AMERICANA; NOSOCOMIAL INFECTIONS; ASPERGILLUS-OCHRACEUS; PATHOGENIC BACTERIA; BLATTELLA-GERMANICA; MEDICAL IMPORTANCE; POTENTIAL VECTORS; SEX-PHEROMONE; antibiotic; food hygiene; jewel wasp | ||||
| Dewey-Dezimal-Klassifikation: | 500 Naturwissenschaften und Mathematik > 540 Chemie 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie 500 Naturwissenschaften und Mathematik > 590 Tiere (Zoologie) | ||||
| Status: | Veröffentlicht | ||||
| Begutachtet: | Ja, diese Version wurde begutachtet | ||||
| An der Universität Regensburg entstanden: | Ja | ||||
| Dokumenten-ID: | 62889 |
Web of ScienceZusammenfassung
Food resources contaminated with spoilage or pathogenic microorganisms pose severe problems to all higher organisms. Here, we describe a food-hygienic strategy of the emerald cockroach wasp Ampulex compressa. The wasp larvae develop on and inside the American cockroach Periplaneta americana, a host that can harbor various putrefactive microbes, as well as human and insect pathogens. From P. ...
Zusammenfassung
Food resources contaminated with spoilage or pathogenic microorganisms pose severe problems to all higher organisms. Here, we describe a food-hygienic strategy of the emerald cockroach wasp Ampulex compressa. The wasp larvae develop on and inside the American cockroach Periplaneta americana, a host that can harbor various putrefactive microbes, as well as human and insect pathogens. From P. americana, we isolated the Gram-negative bacterium Serratia marcescens, which is a potent entomopathogen that can rapidly kill insect larvae. It is also known as a food contaminant and as an opportunistic human pathogen. Using behavioral observations and chemical analyses, we demonstrated that A. compressa larvae impregnate their cockroach hosts from inside with large amounts of an oral secretion containing a blend of gamma-lactones and isocoumarins with (R)-(-)-mellein [(R)-(-)-3,4-diydro-8-hydroxy-3-methylisocoumarin] and micromolide [(4R,9Z)-octadec-9-en-4-olide] as dominant components. We fractionated hexane extracts of the secretion and investigated the antimicrobial properties of the fraction containing the lactones and isocoumarins, as well as of synthetic (R)-(-)-mellein and micromolide, against S. marcescens and a Gram-positive bacterium, Staphylococcus hyicus, in broth microdilution assays. The test fraction inhibited growth of both tested bacteria. The activity of the fraction against S. marcescens was explained by (R)-(-)-mellein alone, and the activity against S. hyicus was explained by the combined action of (R)-(-)-mellein and micromolide. Our data suggest that the specific combination of antimicrobials in the larval secretion provides an effective frontline defense against the unpredictable spectrum of microbes that A. compressa larvae may encounter during their development inside their cockroach hosts.
Metadaten zuletzt geändert: 19 Dez 2024 08:44
Altmetric