Abstract
We describe the reconstruction of a genome-scale metabolic model of the crenarchaeon Sulfolobus solfataricus, a hyperthermoacidophilic microorganism. It grows in terrestrial volcanic hot springs with growth occurring at pH 2-4 (optimum 3.5) and a temperature of 75-80 degrees C (optimum 80 degrees C). The genome of Sulfolobus solfataricus P2 contains 2,992,245 bp on a single circular chromosome ...

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