Cytotoxicity and immunomodulating characteristics of labdane diterpenes from Marrubium cylleneum and Marrubium velutinum

Karioti, Anastasia

; Skopeliti, Margarita ; Tsitsilonis, Ourania ; Heilmann, Jörg ; Skaltsa, Helen

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Zusammenfassung

From the aerial parts of Marrubium cylleneum, one labdane nor-diterpene has been isolated together with two labdane diterpenes, hitherto not known as natural products. The structures of the isolated compounds were established by means of NMR [H-1-H-1-COSY, H-1-C-13-HSQC, HMQC-TOCSY, HMBC, NOESY] and MS spectral analyses. Several diterpenoids from M. cylleneum and M. velutinum were tested for ...