Zusammenfassung
Objective: Functional MRI was used to test the effects of the deficient emotional responsiveness of psychopathic patients on cognitive processes. Method: We used a Simon-paradigm, in which ten healthy volunteers and ten patients with a diagnosis of "psychopathy" (defined by Hare Psychopathy Checklist Revised) have to select their spatially defined responses on the basis of a nonspatial stimuli ...
Zusammenfassung
Objective: Functional MRI was used to test the effects of the deficient emotional responsiveness of psychopathic patients on cognitive processes. Method: We used a Simon-paradigm, in which ten healthy volunteers and ten patients with a diagnosis of "psychopathy" (defined by Hare Psychopathy Checklist Revised) have to select their spatially defined responses on the basis of a nonspatial stimuli feature. For the emotion induction pictures from the international Affective Picture System (IAPS) were selected. At the beginning and intermediated by the Simon-paradigm blocks of positive, negative or neutral pictures were presented. Results: Patients with "psychopathy" exhibited untypical activation patterns in amygdala and prefrontal regions during interferences between negative or positive stimulations and cognitive tasks. Conclusions: These results demonstrated disturbed regulation of emotion-cognition-interaction in "psychopathy" according to PCL-R.
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