Wiesbeck, Gerhard A ; Weijers, Heinz-gerd ; Wodarz, Norbert ; Keller, Heike K ; Michel, Tanja M ; Herrmann, Martin J ; Boening, Jobst
Alternative Links zum Volltext:DOIVerlag
Dokumentenart: | Artikel |
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Titel eines Journals oder einer Zeitschrift: | The World Journal of Biological Psychiatry |
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Verlag: | W F S B P-WORLD FEDERATION SOCBIOLOGICAL PSYCHIATRY |
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Ort der Veröffentlichung: | GLASGOW |
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Band: | 5 |
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Nummer des Zeitschriftenheftes oder des Kapitels: | 1 |
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Seitenbereich: | S. 45-48 |
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Datum: | 2004 |
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Institutionen: | Medizin > Lehrstuhl für Psychiatrie und Psychotherapie |
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Identifikationsnummer: | Wert | Typ |
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10.1080/15622970410029907 | DOI |
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Stichwörter / Keywords: | REGULATORY REGION; TEMPERAMENT; ASSOCIATION; serotonin transporter (5-HTT) gene regulatory region polymorphism; Temperament and Character Inventory (TCI); harm avoidance; primary alcohol dependence |
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Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin |
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Status: | Veröffentlicht |
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Begutachtet: | Ja, diese Version wurde begutachtet |
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An der Universität Regensburg entstanden: | Ja |
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Dokumenten-ID: | 71901 |
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Web of Science
Zusammenfassung
We tested the hypothesis of an association between the serotonin transporter (5-HTT) gene regulatory region polymorphism and the Temperament and Character Inventory (TCI) personality dimension of Harm Avoidance. For the study, 124 subjects seeking inpatient treatment for primary alcohol dependence were grouped by their 5-HTT genotype and assessed with the TCI. Genotypes differed statistically ...
Zusammenfassung
We tested the hypothesis of an association between the serotonin transporter (5-HTT) gene regulatory region polymorphism and the Temperament and Character Inventory (TCI) personality dimension of Harm Avoidance. For the study, 124 subjects seeking inpatient treatment for primary alcohol dependence were grouped by their 5-HTT genotype and assessed with the TCI. Genotypes differed statistically significantly in Harm Avoidance but not in any other personality trait. This gives support to the hypothesis that the TCI temperament Harm Avoidance is associated with serotonergic neuro-transmission in primary alcohol dependence.