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Serotonin transporter gene polymorphism and personality traits in primary alcohol dependence

Wiesbeck, Gerhard A ; Weijers, Heinz-gerd ; Wodarz, Norbert ; Keller, Heike K ; Michel, Tanja M ; Herrmann, Martin J ; Boening, Jobst



Zusammenfassung

We tested the hypothesis of an association between the serotonin transporter (5-HTT) gene regulatory region polymorphism and the Temperament and Character Inventory (TCI) personality dimension of Harm Avoidance. For the study, 124 subjects seeking inpatient treatment for primary alcohol dependence were grouped by their 5-HTT genotype and assessed with the TCI. Genotypes differed statistically ...

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