Alternative Links zum Volltext:DOIVerlag
| Dokumentenart: | Artikel |
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| Titel eines Journals oder einer Zeitschrift: | Psychiatrische Praxis |
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| Verlag: | GEORG THIEME VERLAG KG |
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| Ort der Veröffentlichung: | STUTTGART |
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| Band: | 30 |
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| Seitenbereich: | S. 110-114 |
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| Datum: | 2003 |
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| Institutionen: | Medizin > Lehrstuhl für Psychiatrie und Psychotherapie |
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| Identifikationsnummer: | | Wert | Typ |
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| 10.1055/s-2003-39759 | DOI |
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| Stichwörter / Keywords: | LUMBAR SPINE KINEMATICS; PARKINSONS-DISEASE; HALOPERIDOL; MOVEMENTS; WALKING; PLACEBO; SIGNS; |
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| Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin |
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| Status: | Veröffentlicht |
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| Begutachtet: | Ja, diese Version wurde begutachtet |
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| An der Universität Regensburg entstanden: | Ja |
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| Dokumenten-ID: | 72306 |
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Web of Science
Zusammenfassung
Schizophrenic disorders as well as neuroleptic treatment can affect locomotion. The study assessed the influence of neuroleptic treatment on human gait via ultrasonic topometric gait analysis. In a control sample the test system proved high test-retest-reliability. Spatial and temporal gait parameters were assessed in schizophrenic patients without neuroleptic treatment (n = 12) and under ...
Zusammenfassung
Schizophrenic disorders as well as neuroleptic treatment can affect locomotion. The study assessed the influence of neuroleptic treatment on human gait via ultrasonic topometric gait analysis. In a control sample the test system proved high test-retest-reliability. Spatial and temporal gait parameters were assessed in schizophrenic patients without neuroleptic treatment (n = 12) and under treatment with conventional neuroleptics (n = 14) and re-assessed after treatment change to the atypical neuroleptic olanzapine in a repeated measures design. After switch from conventional neuroleptics to olanzapine patients showed an increase of gait velocity (p less than or equal to 0.01) and step length (p less than or equal to 0.01) whereas the cadence remained stable. Significant differences between the untreated state and treatment with olanzapine were not detectable. We conclude that bipedal gait is affected by conventional neuroleptic treatment. The degree of impairment can be objectively measured by testing spatio-temporal and kinematic gait parameters via three-dimensional ultrasonic gait analysis.
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