Plasmodium blood stage development requires the chromatin remodeller Snf2L

URN to cite this document:: urn:nbn:de:bvb:355-epub-750499
DOI to cite this document:: 10.5283/epub.75049

Watzlowik, Maria Theresia ; Silberhorn, Elisabeth ; Das, Sujaan

; Singhal, Ritwik ; Venugopal, Kannan ; Holzinger, Simon

; Stokes, Barbara ; Schadt, Ella ; Sollelis, Lauriane ; Bonnell, Victoria A. ; Gow, Matthew ; Klingl, Andreas ; Marti, Matthias ; Llinás, Manuel ; Meissner, Markus ; Längst, Gernot

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Date of publication of this fulltext: 24 Feb 2025 09:38

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Abstract

The complex life cycle of the malaria parasite Plasmodium falciparum involves several major differentiation stages, each requiring strict control of gene expression. Fundamental changes in chromatin structure and epigenetic modifications during life cycle progression suggest a central role for these mechanisms in regulating the transcriptional program of malaria parasite development1,2,3,4,5,6. ...