; Reinoso-Schiller, Nicolas ; Maričić, Lea Mascarell ; Röcher, Erik ; Kalman, Janos L. ; Stroth, Sanna
; Mayer, Annalina V.
; Schwarz, Kristina ; Kaiser, Anna ; Pfennig, Andrea ; Manook, André ; Ising, Marcus ; Heinig, Ingmar ; Pittig, Andre
; Heinz, Andreas
; Mathiak, Klaus ; Schulze, Thomas G. ; Schneider, Frank
; Kamp-Becker, Inge ; Meyer-Lindenberg, Andreas ; Padberg, Frank ; Banaschewski, Tobias ; Bauer, Michael ; Rupprecht, Rainer ; Wittchen, Hans-Ulrich ; Rapp, Michael A. 
| Dokumentenart: | Artikel | ||||
|---|---|---|---|---|---|
| Titel eines Journals oder einer Zeitschrift: | European Archives of Psychiatry and Clinical Neuroscience | ||||
| Verlag: | SPRINGER HEIDELBERG | ||||
| Ort der Veröffentlichung: | HEIDELBERG | ||||
| Band: | 273 | ||||
| Nummer des Zeitschriftenheftes oder des Kapitels: | 3 | ||||
| Seitenbereich: | S. 527-539 | ||||
| Datum: | 2023 | ||||
| Institutionen: | Medizin > Lehrstuhl für Psychiatrie und Psychotherapie | ||||
| Identifikationsnummer: |
| ||||
| Stichwörter / Keywords: | CONSTRUCTS; FRAMEWORK; PSYCHOPATHOLOGY; SCHIZOPHRENIA; OPPORTUNITIES; ANHEDONIA; VERSION; Diagnosis and classification; Research Domain Criteria; PD-CAN; Confirmatory factor analysis CFA; RDoC; Transdiagnostic | ||||
| Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin | ||||
| Status: | Veröffentlicht | ||||
| Begutachtet: | Ja, diese Version wurde begutachtet | ||||
| An der Universität Regensburg entstanden: | Ja | ||||
| Dokumenten-ID: | 75381 |
Zusammenfassung
This study aimed to build on the relationship of well-established self-report and behavioral assessments to the latent constructs positive (PVS) and negative valence systems (NVS), cognitive systems (CS), and social processes (SP) of the Research Domain Criteria (RDoC) framework in a large transnosological population which cuts across DSM/ICD-10 disorder criteria categories. One thousand four ...

Zusammenfassung
This study aimed to build on the relationship of well-established self-report and behavioral assessments to the latent constructs positive (PVS) and negative valence systems (NVS), cognitive systems (CS), and social processes (SP) of the Research Domain Criteria (RDoC) framework in a large transnosological population which cuts across DSM/ICD-10 disorder criteria categories. One thousand four hundred and thirty one participants (42.1% suffering from anxiety/fear-related, 18.2% from depressive, 7.9% from schizophrenia spectrum, 7.5% from bipolar, 3.4% from autism spectrum, 2.2% from other disorders, 18.4% healthy controls, and 0.2% with no diagnosis specified) recruited in studies within the German research network for mental disorders for the Phenotypic, Diagnostic and Clinical Domain Assessment Network Germany (PD-CAN) were examined with a Mini-RDoC-Assessment including behavioral and self-report measures. The respective data was analyzed with confirmatory factor analysis (CFA) to delineate the underlying latent RDoC-structure. A revised four-factor model reflecting the core domains positive and negative valence systems as well as cognitive systems and social processes showed a good fit across this sample and showed significantly better fit compared to a one factor solution. The connections between the domains PVS, NVS and SP could be substantiated, indicating a universal latent structure spanning across known nosological entities. This study is the first to give an impression on the latent structure and intercorrelations between four core Research Domain Criteria in a transnosological sample. We emphasize the possibility of using already existing and well validated self-report and behavioral measurements to capture aspects of the latent structure informed by the RDoC matrix.
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