| Lizenz: Creative Commons Namensnennung 4.0 International PDF - Veröffentlichte Version (13MB) |
- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-767081
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.76708
Zusammenfassung
To investigate the early, poorly understood events driving metastatic progression, we searched for the earliest detectable disseminated cancer cells (DCCs), also often referred to as disseminated tumor cells (DTCs), in sentinel lymph node (SLN) biopsies of 492 patients with stage I–III melanoma. Using micromanipulator-assisted isolation of rare DCCs, single-cell mRNA and DNA sequencing, ...

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