| Lizenz: Creative Commons Namensnennung 4.0 International PDF - Veröffentlichte Version (9MB) |
- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-768166
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.76816
Zusammenfassung
Photoswitchable unnatural amino acids are valuable engineering tools in biotechnology, particularly for the reversible control of enzymes with light. Here, we explore some basic principles of this protein engineering technique to simplify its approach and increase its success rate. To this end, we have selected Escherichia coli type II asparaginase (EcAII), which is a prominent chemotherapeutic ...

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