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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-770385
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.77038
Zusammenfassung
T cells equipped with chimeric antigen receptors (CARs) have evolved into an essential pillar of lymphoma therapy, reaching second-line treatment. In solid cancers, however, a dearth of lasting CAR T cell activation poses the major obstacle to achieving a substantial and durable anti-tumor response. To extend T cell cytotoxic capacities, we engineered CAR T cells to constitutively release an ...
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