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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-777093
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.77709
Zusammenfassung
In adaptive clinical trials, the conventional confidence interval (CI) for a treatment effect is prone to undesirable properties such as undercoverage and potential inconsistency with the final hypothesis testing decision. Accordingly, as is stated in recent regulatory guidance on adaptive designs, there is the need for caution in the interpretation of CIs constructed during and after an adaptive ...
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