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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-778559
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.77855
Zusammenfassung
One family of designs that can noticeably improve efficiency in later stages of drug development are multi-arm multi-stage (MAMS) designs. They allow several arms to be studied concurrently and gain efficiency by dropping poorly performing treatment arms during the trial as well as by allowing to stop early for benefit. Conventional MAMS designs were developed for the setting, in which treatment ...

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