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Anzahl der Einträge: 14.
2024
Jaki, Thomas 
, Barnett, Helen, Titman, Andrew und Mozgunov, Pavel
(2024)
A seamless Phase I/II platform design with a time-to-event efficacy endpoint for potential COVID-19 therapies.
Statistical Methods in Medical Research 33 (11-12), S. 2115-2130.
Barnett, Helen, George, Matthew, Skanji, Donia, Saint-Hilary, Gaelle, Jaki, Thomas und Mozgunov, Pavel
(2024)
A comparison of model-free phase I dose escalation designs for dual-agent combination therapies.
Statistical Methods in Medical Research 33 (2), S. 203-226.
2023
Serra, Alessandra , Mozgunov, Pavel, Davies, Geraint und Jaki, Thomas
(2023)
Determining the minimum duration of treatment in tuberculosis: An order restricted non‐inferiority trial design.
Pharmaceutical Statistics 22 (5), S. 938-962.
Jaki, Thomas , Burdon, Abigail , Chen, Xijin , Mozgunov, Pavel, Zheng, Haiyan und Baird, Richard
(2023)
Early phase clinical trials in oncology: Realising the potential of seamless designs.
European Journal of Cancer 189, S. 112916.
Serra, Alessandra , Mozgunov, Pavel und Jaki, Thomas
(2023)
A Bayesian multi‐arm multi‐stage clinical trial design incorporating information about treatment ordering.
Statistics in Medicine 42 (16), S. 2841-2854.
Robertson, David S., Choodari‐Oskooei, Babak, Dimairo, Munya , Flight, Laura, Pallmann, Philip und Jaki, Thomas
(2023)
Point estimation for adaptive trial designs II: Practical considerations and guidance.
Statistics in Medicine 42 (14), S. 2496-2520.
Barnett, Helen, Boix, Oliver, Kontos, Dimitris und Jaki, Thomas
(2023)
Backfilling cohorts in phase I dose-escalation studies.
Clinical Trials 20 (3), S. 261-268.
Volltext nicht vorhanden.
(2023)
Backfilling cohorts in phase I dose-escalation studies.
Clinical Trials 20 (3), S. 261-268.
Volltext nicht vorhanden.
2022
Robertson, David S., Choodari‐Oskooei, Babak, Dimairo, Munya, Flight, Laura, Pallmann, Philip und Jaki, Thomas
(2022)
Point estimation for adaptive trial designs I: a methodological review.
Statistics in Medicine 42 (2), S. 122-145.
Wason, James M. S., Dimairo, Munyaradzi, Biggs, Katie, Bowden, Sarah, Brown, Julia, Flight, Laura, Hall, Jamie, Jaki, Thomas , Lowe, Rachel, Pallmann, Philip, Pilling, Mark A., Snowdon, Claire, Sydes, Matthew R., Villar, Sofía S., Weir, Christopher J., Wilson, Nina, Yap, Christina, Hancock, Helen und Maier, Rebecca
(2022)
Practical guidance for planning resources required to support publicly-funded adaptive clinical trials.
BMC Medicine 20, S. 254.
Lee, Kim May, Robertson, David S., Jaki, Thomas und Emsley, Richard
(2022)
The benefits of covariate adjustment for adaptive multi-arm designs.
Statistical Methods in Medical Research 31 (11), S. 2104-2121.
Serra, Alessandra, Mozgunov, Pavel, Jaki, Thomas und Rigat, Fabio
(2022)
What is the expected benefit of patient-centric clinical development in oncology?
Journal of Biopharmaceutical Statistics 32 (3), S. 414-426.
Serra, Alessandra, Mozgunov, Pavel und Jaki, Thomas
(2022)
An order restricted multi‐arm multi‐stage clinical trial design.
Statistics in Medicine 41 (9), S. 1613-1626.
2021
Mozgunov, Pavel, Cro, Suzie, Lingford‐Hughes, Anne, Paterson, Louise M. und Jaki, Thomas
(2021)
A dose‐finding design for dual‐agent trials with patient‐specific doses for one agent with application to an opiate detoxification trial.
Pharmaceutical Statistics 21 (2), S. 476-495.
Barnett, Helen Yvette, Villar, Sofía S., Geys, Helena und Jaki, Thomas
(2021)
A novel statistical test for treatment differences in clinical trials using a response‐adaptive forward‐looking Gittins Index Rule.
Biometrics 79 (1), S. 86-97.
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