| Lizenz: Creative Commons Namensnennung 4.0 International PDF - Veröffentlichte Version (7MB) |
- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-780825
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.78082
Zusammenfassung
Adenoviruses are human pathogens that more recently have gathered interest as tools for human gene therapy and vaccination. The maturation of the viral genome with associated proteins (core) remains largely unexplored. Here, we show that adenovirus core maturation is guided by features embedded in the viral DNA sequence, which primes the genome for transcription. Using DMS-seq to compare the ...

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