Zusammenfassung
Health and social care systems currently undergo a transformation from phenomenological through
evidence-based, person-centered, and personalized care towards personalized, preventive, predictive,
participative precision medicine (5PM), supported by technology. 5PM considers individual health status,
conditions, genetic and genomic dispositions in personal social, occupational, environmental ...
Zusammenfassung
Health and social care systems currently undergo a transformation from phenomenological through
evidence-based, person-centered, and personalized care towards personalized, preventive, predictive,
participative precision medicine (5PM), supported by technology. 5PM considers individual health status,
conditions, genetic and genomic dispositions in personal social, occupational, environmental and behavioral
context, that way understanding the pathology of diseases and turning health and social care from reactive
to proactive. Thereby, we have to enable communication and cooperation between all actors of the
ecosystem, participating in different knowledge spaces, representing different disciplines, using different
methodologies, perspectives, intentions, languages, etc. Therefore, the knowledge-based, multidisciplinary,
highly complex and dynamic 5PM ecosystem must be consistently and formally represented. The outcome
is a system-theoretical, architecture-centric, ontology-based, policy-driven approach for designing and
managing intelligent and sustainable 5PM ecosystems, developed by the author and meanwhile standardized
as ISO 23903 Health informatics – Interoperability and Integration Reference Architecture – Model and
Framework. The deployment of that standard is meanwhile mandatory for all projects at ISO, CEN, HL7, IEEE,
etc., addressing more than one domain.