Zusammenfassung
Healthcare systems around the world are undergoing
an organizational, methodological and technological
transformation towards Personalized, Preventive,
Predictive, Participative Precision (5P) medicine
ecosystems. These ecosystems consider individual health
status, conditions, genetic and genomic dispositions
in personal social, occupational, environmental, and
behavioral contexts. For ...
Zusammenfassung
Healthcare systems around the world are undergoing
an organizational, methodological and technological
transformation towards Personalized, Preventive,
Predictive, Participative Precision (5P) medicine
ecosystems. These ecosystems consider individual health
status, conditions, genetic and genomic dispositions
in personal social, occupational, environmental, and
behavioral contexts. For designing and managing the
resulting highly interdisciplinary, complex, distributed and
dynamic ecosystem, we must formally and consistently
represent the system and its components at necessary
granularity levels from the perspective of all actors
including the subject of care. As those actors from
different domains have different education, skills, and
experiences, using different methodologies, languages
and terminologies, communication and cooperation, i.e.
interoperability, must advance from the data level (data
sharing) to the knowledge level (knowledge sharing).
To understand the business system, it must formally
represent each considered use case structurally and
functionally. Therefore, the design, implementation
and management of intelligent and ethical transformed
ecosystems must be realized, using a system-theoretical,
architecture-centered, ontology-based and policy-driven approach, developed by the author
over the last 30 years. The related model and framework has been meanwhile standardized as
the ISO 23903 Interoperability and Integration Reference Architecture, defined as mandatory
for any specification or project at ISO, CEN, IEEE, OMG, etc., addressing more than one
domain. Thereby, it manages also security, privacy and trust in detail. The Keynote introduces
necessary standards and methodologies for designing and managing 5P medicine ecosystems as well as practical examples.