Zusammenfassung
Healthcare systems around the world are
undergoing an organizational, methodological and
technological transformation towards personalized,
preventive, predictive, participative precision (5P)
medicine ecosystems. These ecosystems consider
individual health status, conditions, genetic and
genomic dispositions in personal social, occupational,
environmental, and behavioral contexts. ...
Zusammenfassung
Healthcare systems around the world are
undergoing an organizational, methodological and
technological transformation towards personalized,
preventive, predictive, participative precision (5P)
medicine ecosystems. These ecosystems consider
individual health status, conditions, genetic and
genomic dispositions in personal social, occupational,
environmental, and behavioral contexts. Thereby, we
have to consider and fully understand the clinical case
from the perspective of all involved disciplines from
elementary particles up to the society. For designing
and managing the resulting highly interdisciplinary,
complex, distributed and dynamic ecosystem, we
must formally and consistently represent the system
and its components at necessary granularity levels
from the perspective of all actors including the subject
of care. As those actors from different domains have
different education, skills, and experiences, using
different methodologies, languages and terminologies,
communication and cooperation, i.e. interoperability,
must advance from the data level (data sharing) to the
knowledge level (knowledge sharing). To understand
the business system, it must formally represent each considered use case structurally and
functionally. Therefore, the design, implementation and management of intelligent and
ethical transformed ecosystems must be realized, using a system-theoretical, architecturecentered,
ontology-based and policy-driven approach, developed by the author over the last
30 years. The related model and framework has been meanwhile standardized as the ISO
23903 Interoperability and Integration Reference Architecture, defined as mandatory for any
specification or project at ISO, CEN, IEEE, OMG, etc., addressing more than one domain.
Thereby, it manages also security, privacy and trust in detail. The Keynote introduces necessary
standards and methodologies for designing and managing 5P medicine ecosystems as well as
practical examples.
Weitere Literatur (mittels CORE)