Zusammenfassung
Advancing from phenomenological, evidence-based, person-centered, and personalized care, health
ecosystems currently undergo a transformation towards personalized, preventive, predictive, participative
precision medicine (5PM), supported by technology. It considers individual health status, conditions,
genetic and genomic dispositions in personal social, occupational, environmental and ...
Zusammenfassung
Advancing from phenomenological, evidence-based, person-centered, and personalized care, health
ecosystems currently undergo a transformation towards personalized, preventive, predictive, participative
precision medicine (5PM), supported by technology. It considers individual health status, conditions,
genetic and genomic dispositions in personal social, occupational, environmental and behavioral context,
understanding the pathology of diseases and turning health and social care from reactive to proactive.
Thereby, we have to enable communication and cooperation between all actors from different knowledge
spaces including the subject of care, representing different disciplines, using different methodologies,
perspectives, intentions, languages, etc., based on different educations and skills. Therefore, the knowledgebased,
multidisciplinary, highly complex and highly dynamic 5PM ecosystem must be consistently and
formally represented. The outcome is a system-theoretical, context-sensitive, architecture-centric,
ontology-based, policy-driven approach for designing and managing intelligent, ethical and sustainable
5PM ecosystems, developed by the author and internationally standardized. The deployment of the
approach is meanwhile defined by leading standards developing organizations such as ISO, CEN, IEEE,
etc., as mandatory for all projects covering more than just one domain.