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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-790110
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.79011
Zusammenfassung
We previously reported a loss of T cell activation following knockdown of the phospholipid scramblase and ion channel ANO9 (TMEM16J) in human Jurkat lymphocytes. We have now analyzed in detail the role of ANO9 in Jurkat ANO9 knockout cells and primary human pan-T cells. In addition, transgenic knockin mice carrying the T595A-Ano9 mutation were generated, as the human counterpart T604A-ANO9 and ...
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